DCM 2010 provides a forum for ideas about new computing means and models, with a particular emphasis in 2010 on computational and causal models related to physics and biology. We believe that bringing together different approaches - in a community with the strong foundational background characteristic of FLoC - results in inspirational cross-boundary exchanges, and innovative further research. Day two of this pre-FLoC 2010 workshop is given over to physics and quantum related computation. The content of day one is more typical of previous DCM workshops - covering a full spectrum of topics related to the development of new computational models or new features for traditional computational models. DCM 2010 was designed to foster interactions, and provide a forum for presenting new ideas and work in progress. It is also intended to enable newcomers to learn about current research in this area.