In this paper, we use statistical tools to analysis dependency between Wireless Sensor Network (WSN) parameters and overall Energy Consumption (EC). Our approach has two main phases: profiling, and effective parameter extraction. In former, a sensor network simulator is re-run 800 times with different values for eight WSN parameters to profile consumed energy in nodes; then in latter, three statistical analyses (p-value, linear and non-linear correlation) are applied to the outcome of profiling phase to extract the most effective parameters on WSN overall energy consumption.