The performance of active disturbance rejection control (ADRC) algorithms can be limited in practice by high-frequency measurement noise. In this work, this problem is addressed by transforming the high-gain extended state observer (ESO), which is the inherent element of ADRC, into a new cascade observer structure. Set of experiments, performed on a DC-DC buck power converter system, show that the new cascade ESO design, compared to the conventional approach, effectively suppresses the detrimental effect of sensor noise over-amplification while increasing the estimation/control performance. The proposed design is also analyzed with a low-pass filter at the converter output, which is a common technique for reducing measurement noise in industrial applications.