As Industry 4.0 and digitalization continue to advance, the reliance on information technology increases, making the world more vulnerable to cyber-attacks, especially cyber-physical attacks that can manipulate physical systems and compromise operational data integrity. Detecting cyber-attacks in multistage manufacturing systems (MMS) is crucial due to the growing sophistication of attacks and the complexity of MMS. Attacks can propagate throughout the system, affecting subsequent stages and making detection more challenging than in single-stage systems. Localization is also critical due to the complex interactions in MMS. To address these challenges, a group lasso regression-based framework is proposed to detect and localize attacks in MMS. The proposed algorithm outperforms traditional hypothesis testing-based methods in expected detection delay and localization accuracy, as demonstrated in a linear multistage manufacturing system.